Vladimir P. Torchilin, Ph.D., D.Sc.
Distinguished Professor and Chairman, Department of Pharmaceutical Sciences, and Director, Center for Pharmaceutical Biotechnology and Nanomedicine, School of Pharmacy, Bouve College of Health Sciences, Northeastern University

Address: Department of Pharmaceutical Sciences
School of Pharmacy
Bouve College of Health Sciences
Northeastern University
Mugar Building, Rm 312
360 Huntington Avenue
Boston, MA 02129
Tel: (617) 373-3206; FAX: (617) 373-8886; e-mail: v.torchilin@neu.edu

Education:
M.S. in Polymer Chemistry from Moscow State University, Moscow, Russia, 1968
Ph.D. in Chemical Kinetics and Catalysis from Moscow State University, Moscow, Russia, 1971
D.Sc. in Bioorganic Chemistry from Moscow State University, Moscow, Russia, 1980
Since 1985 - Professor in Bioorganic Chemistry, Chemistry of Natural and
Physiologically Active Compounds

Academic Appointmens:
1971-1973 Junior Scientist, Moscow State University
1974-1980 Senior Scientist, Academy of Medical Sciences of the USSR
1985-1991 Professor of Biochemistry, Academy of Medical Sciences of the USSR
1989-1991 Professor in Biotechnology, Lomonosov Institute of Fine Chemical
Technology, Moscow, USSR
1991 Visiting Professor of Biochemistry, University of Tennessee
1991 Visiting Professor, University of California, San Diego
1993-1999 Associate Professor of Radiology, Harvard Medical School
1998- Professor of Pharmaceutical Sciences, Northeastern University
2004- Distinguished Professor of Pharmaceutical Sciences, Northeastern University
2005- Director, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University

Awards and Honors:
1982 Lenin Prize of the USSR in Science and Technology (the highest
scientific award in the former USSR)
1978, 82, 85 Exchange Scientist, US/USSR Exchange Prograrn in Cardiovascular
87,89, 90 Research - Myocardial Metabolism
1991 Full member (Academician), Russian Academy of Biotechnology
1994 1993 Outstanding Pharmaceutical Paper Award, Controlled Release
Society
1994 1993 Outstanding Paper Award from the Journal of Controlled Release
Board of Governors, Controlled Release Society
Co-Chair, 26th International Symposium on Controlled Release of
Biologically Active Materials
2001,03,04,07 Creativity Awards from Northeastern University
2002 Co-Chair, Gordon Research Conference on Drug Carriers in Biology and
Medicine
2002 Fellow, American Institute for Medical and Biological Engineering
2002 Innovation Award from Northeastern University
2002 Member, European Academy of Sciences
2003 Vice President, Controlled Release Society
2003 Fellow, American Association of Pharmaceutical Scientists (AAPS)
2003 ATOMS Research Excellence in Mentorship Award, National Institute of
General Medical Sciences
2004 Distinguished Northeastern University Professor of Pharmaceutical Sciences
2004 Member, Board of Directors, International Liposome Society
2005 President, Controlled Release Society
2005 Founding Member, American Academy of Nanomedicine
2005 Research Achievements Award in Pharmaceutics and Drug Delivery, AAPS
2005 The Joy Goodwin Lecturer, Auburn University
2005 Member, Research and Graduate Affairs Committee, AACP
2006 2006 CRS-Baxter Healthcare Outstanding Parenteral Drug Delivery Award (with postdoc,
T.Elbayoumi)
2006 The Massachusetts Technology Transfer Center 2006 Investigation Award
2007 Research Achievements Award from the World Pharmaceutical Congress, Amsterdam
2007 Phi Beta Delta

Editorial Boards:
1979-1986 Enzyme Microbial Technology
1984-1995 Journal of Controlled Release
1987- Advanced Drug Delivery Reviews
1988-1996 Hemostasis
1989-1992 Biokhimia (Russian)
1989- Journal of Microencapsulation
1990- Bioconjugate Chemistry
1992- Journal of Liposome Research
1995- Journal of Drug Targeting
1999- Journal of Controlled Release, Review Editor
1999- European Journal of Pharmaceutics and Biopharmaceutics
2002- Journal of Bioactive and Compatible Polymers
2003- Molecular Pharmaceutics
2003- Current Drug Delivery
2003- Drug Discovery Today
2004- Chinese Journal of Interventional Imaging and Therapy
2004- Journal of Biomedical Nanotechnology
2004- Expert Opinion on Drug Delivery
2004- Current Protein and Peptide Science
2005- International Journal of Nanomedicine
2005- Journal of Biopharmaceutics and Biotechnology
2005- Nanotechnology, Diagnostics, and Therapeutics (web journal from
BioMedCentral)

Co-founder:
Oncologic Biopahramceuticals
MitoVec Inc.
Encapsion Inc.

SAB member and/or Consultant for:
Labopharm Inc.
Genzyme Corp.
Procyon Biopharma Inc.
Boston Life Sciences Inc.
Endorex Inc.
Oncologic
MitoVec Inc.
PureTech
Nanopharma
CellGate Inc.
LigoCyte Inc.
Eurand
Oral Vaccine Institute
Encapsion
Solubest

MAJOR RESEARCH INTERESTS:
1. Physiologically active polymers and their use as drug carriers. Polymeric drugs. Slow release
systems. Pharmacokinetics and biodistribution of slow release drugs.
2. Various systems for controlled delivery of pharmaceuticals including macromolecular drugs,
DNA, and imaging agents.
3. Targeted delivery of therapeutic and diagnostic agents. Tumor targeting and targeting within
the cardiovascular system.
4. Physico-chemical aspects of enzyme stabilization and immobilization on polymeric carriers.
Therapeutic enzymes. Experimental thrombolytic therapy.
5. Artificial phospholipid membranes. Liposomes, their physico-chemical and biological
properties. Long-circulating and polymer-modified liposomes as drug carriers. Immunoliposomes. Protein binding with liposomes. Liposome-cell interactions. Pharmacokinetics of liposomes.
6. Micellar solubilization of poorly soluble drugs. Polymeric micelles. Targeted micelles. Immunomicelles. Micellar tumor targeting.
7. Experimental diagnostic imaging. Contrast agents for gamma-imaging, magnetic resonance
imaging and computed tomography. Labeling of polymers, proteins (antibodies and their
fragments), and microparticulates (liposomes, nanoparticles, micelles) with diagnostic metal
isotopes via chelating groups. Chelating polymers for heavy loading antibodies with metal isotopes. Amphiphilic chelating polymers as key components of liposomal and micellar imaging agents. Iodine-containing long-circulating micelles for computed tomography.
8. Experimental tumor immunology and therapy. Intratumor delivery of drugs and imaging
agents. Tumoricidal antibodies. Accumulation of long-circulating drugs in tumors.