PROF. YILMAZ ÇAPAN

Head of Department of Pharmaceutical Technology
President of FATUM (Pharmaceutical Technology Research and Application Center)

Hacettepe University                                           Faculty of Pharmacy
Department of Pharmaceutical Technology 
06100 Ankara- TURKEY                                             
Telephone: 90 312 305 12 41
Fax: 90 312 311 47 77
e-mail: ycapan@hacettepe.edu.tr

EDUCATION

RESEARCH
Prof. Çapan has served as Registration Main Commission member and Commission for BY/BE member at the Turkish Ministry of Health-Drug and Pharmacy General Directorate for several years. He is currently serving as Head of Department of Pharmaceutical Technology since February 2007 and president of FATUM Pharmaceutical Technology Research and Application Center in Hacettepe University since April 2007. Prof. Çapan’s research interests include brain delivery with nanoparticles, brain drug targeting, bioavailability-bioequivalence, controlled release of oral drug delivery systems, tabletting, bioadhesion, GMP and quality assurance, peptide delivery from biodegradable microspheres. Prof. Çapan has been working as visiting scientist and visiting professor in University of Louis Pasteur in Strasbourg, France and University of Kentucky at Lexington, USA. He is also serving as Turkish delegate at the Commission for European Pharmacopeia in Strasbourg.

EXPERIENCE

RESEARCH
Prof. Çapan has served as Registration Main Commission member and Commission for BY/BE member at the Turkish Ministry of Health-Drug and Pharmacy General Directorate for several years. He is currently serving as Head of Department of Pharmaceutical Technology since February 2007 and president of FATUM Pharmaceutical Technology Research and Application Center in Hacettepe University since April 2007. Prof. Çapan’s research interests include brain delivery with nanoparticles, brain drug targeting, bioavailability-bioequivalence, controlled release of oral drug delivery systems, tabletting, bioadhesion, GMP and quality assurance, peptide delivery from biodegradable microspheres. Prof. Çapan has been working as visiting scientist and visiting professor in University of Louis Pasteur in Strasbourg, France and University of Kentucky at Lexington, USA. He is also serving as Turkish delegate at the Commission for European Pharmacopeia in Strasbourg.
    
PROFESSIONAL / HONORY SOCIETES
AAPS                        :  American Association of Pharmacetical Scientists
FABAD                        :  Assoc. of Pharmaceutical Sciences of Ankara
TÜFTAD            :  Turkish Pharmaceutical Technology Scientists' Association
TEB                :  Turkish Pharmacists' Association
AEO               :  Pharmacist's  Chamber of Ankara
CRS                        :  Controlled Release Society
President  of  the  Alumni  Association  of  Faculty  of  Pharmacy,
Hacettepe  University, 1992-1998

Selected Publications from 2000
-Y. Çapan, G. Jiang, S. Giovagnoli, K. Na, P. P. DeLuca, Preparation and characterization of poly(D,L- lactide-co-glycolide) microspheres for controlled release of human growth hormone, AAPS PhamSciTech,  4, 236 (2003).
-S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal,
In vitro Cytotoxıcıty of Mitoxantron-Incorporated Albumin Microspheres on Acute Promyelocytic Leukemia Cells, Journal of Microencapsulation, 21,751 (2004)
-S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal, P.P.DeLuca, Formulation and In Vitro Cytotoxicity of Mitoxantron- Loaded Biodegradable Microspheres on  Rat Glioma Cells, J. Drug Del. Sci. Tech., 15, 201 ( 2005 )
-Y.Aktas, K.Andrieux, M.J.Alonso, P.Calvo, R.N.Gursoy, P.Couvreur, Y.Capan, Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor, Int J Pharm. 298,378 (2005)
-A.C. Kilic, Y. Capan, I. Vural, R. N. Gursoy, T. Dalkara, A. Cuine, A. Hincal, Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-spesific antisense oligonucleotides to the NMDA receptors in the brain, J Microencapsul.  22,633(2005)
-M. Cetin  , Y.Capan , İ.Vural  , L.A.Dogan  , D.Guc  , A.A.Hincal , P.Wehrlé , T.Dalkara , P.P.DeLuca, Preparation and Characterization of bFGF and BSA Loaded Microspheres, J.Drug Del. Sci. Tech.15,371 (2005)
-Aktas Y, Yemisci M, Andrieux K, Gursoy RN, Alonso MJ, Fernandez-Megia E, Novoa-Carballal R, Quinoa E, Riguera R, Sargon MF, Celik HH, Demir AS, Hincal AA, Dalkara T, Capan Y, Couvreur P, Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26, Bioconjug. Chem.,16,1503(2005)
-M.Yemisci, İ.Vural, S. Bozdağ, M. Çetin, F. Söylemezoğlu, Y. Çapan, T. Dalkara, Treatment of Malignant Glioma with Mitoxantrone-Loaded PLGA Microspheres, Neurosurgery. 59 ,1296 (2006)